The inaugural International Research Conference on Smart Computing and Systems Engineering (SCSE), organized by the Department of Industrial Management, Faculty of Science, University of Kelaniya in conjunction with the Ministry of Science, Technology and Research, was successfully held on the 29th March, 2018, at the Hotel Clarion, Kiribathgoda. The conference also had industry partnerships from the Zone 24x7, and the Information and Communication Technology Agency (ICTA). The vice chancellor of University of Kelaniya, Prof. D.M. Semasinghe graced the conference as the chief guest, which was attended by a number of international scholars from foreign universities including Tokyo Institute of Technology (Japan), Tsukuba University (Japan), Yamaguchi University (Japan), Deakin University (Australia), Western Sydney University (Australia) and National Chung Hsing University (Taiwan). The conference showcased research from both Sri Lankan and international researchers in the domains of Smart Computing and Systems Engineering. The keynote addresses for the conference were delivered by Prof. Takao Terano of the Tokyo Institute of Technology, and Prof. Pubudu Pathirana, Director of Networked Sensing and Control (NSC) Research group at the Deakin University. The Dean of Faculty of Science, Prof. (Mrs.) B.M. Jayawardena, Dean of Faculty of Humanities, Prof. Patrick Ratnayake, and Heads of Departments of Faculty of Science also attended the conference.